If you do not experience any significant pain relief from an initial lidocaine infusion, you will receive the same dosage for the next two to three appointments; this is because some patients respond more slowly to the treatment than others and, therefore, require multiple treatments for an effective response. If, after these follow-up treatments, you are still not experiencing significant pain relief, your dosage will be adjusted. Once your appropriate dosage is determined, the treatment can be repeated every three to four weeks, as needed.